lasmiditan, pentobarbital. Either boosts effects of another by sedation. Use Warning/Keep track of. Coadministration of lasmiditan and various CNS depressant medicine, such as alcohol haven't been evaluated in scientific experiments. Lasmiditan might lead to sedation, and also other cognitive and/or neuropsychiatric adverse reactions.
Keep track of Carefully (one)pentobarbital will lower the level or impact of osilodrostat by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will minimize the extent or effect of tamoxifen by influencing hepatic enzyme CYP2C9/10 metabolism. Use Warning/Watch.
Contraindicated (1)pentobarbital will lessen the level or outcome of lonafarnib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Lonafarnib is usually a delicate CYP3A4 substrate. Coadministration with solid or average CYP3A4 inducers is contraindicated.
Monitor Carefully (1)pentobarbital will lessen the level or outcome of mestranol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will minimize the level or effect of zolpidem by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Unidentified.
Contraindicated (1)pentobarbital will reduce the extent or result of lumacaftor/ivacaftor by affecting read more hepatic/intestinal enzyme CYP3A4 metabolism.
Contraindicated (1)pentobarbital will lower the extent or outcome of cariprazine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. CYP3A4 is answerable for the development and elimination of cariprazine's Energetic metabolites.
pentobarbital will reduce the extent or result of nisoldipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
Sodium valproate and valproic acid look to lessen barbiturate metabolism; consequently, barbiturate blood degrees really should be monitored and suitable dosage changes designed as indicated.
pentobarbital will lessen the extent or effect of paclitaxel by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Not known.
pentobarbital will lessen the extent or effect of etravirine by affecting hepatic enzyme CYP2C9/10 metabolism. Use Caution/Keep track of.
pentobarbital will lessen the level or result of mavacamten by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
Phenobarbital appears to interfere While using the absorption of orally administered griseofulvin, So reducing its blood degree.